TY - T1 - Bacterial Extracellular Vesicles in Gastrointestinal Tract Cancer : An Unexplored Territory SN - / UR - http://hdl.handle.net/10138/337457 T3 - A1 - Amatya, Sajeen Bahadur; Salmi, Sonja; Kainulainen, Veera; Karihtala, Peeter; Reunanen, Justus A2 - PB - Y1 - 2021 LA - eng AB - Simple Summary:& nbsp;Microbial dysbiosis has been credited as one of the contributing factors to the development and progression of gastrointestinal tract cancer. The altered microbiota influences carcinogenesis through the induction of instability and damage to genetic material, modulation of host metabolic and inflammatory pathways, production of carcinogenic metabolites, and suppression of host antitumor response. These microbes secrete extracellular vesicles that are possibly carrying carci... VO - IS - SP - OP - KW - gastrointestinal tract; microbiota; extracellular vesicles; cancer; OUTER-MEMBRANE-VESICLES; GRAM-NEGATIVE BACTERIA; ESCHERICHIA-COLI; FUSOBACTERIUM-NUCLEATUM; PORPHYROMONAS-GINGIVALIS; PSEUDOMONAS-AERUGINOSA; COLORECTAL-CANCER; GUT MICROBIOTA; PERIPLASMIC PROTEINS; HELICOBACTER-PYLORI; 3122 Cancers N1 - PP - ER -