TY - T1 - Baseline Predictors of High Adherence to a Coitally Dependent Microbicide Gel Based on an Objective Marker of Use : Findings from the Carraguard Phase 3 Trial SN - / UR - http://hdl.handle.net/10138/169638 T3 - A1 - Friedland, Barbara A.; Stoner, Marie; Chau, Michelle M.; Plagianos, Marlena Gehret; Govender, Sumen; Morar, Neetha; Altini, Lydia; Skoler-Karpoff, Stephanie; Ahmed, Khatija; Ramjee, Gita; Monedi, Constance; Maguire, Robin; Lähteenmäki, Pekka A2 - PB - Y1 - 2016 LA - eng AB - A randomized, placebo-controlled, efficacy trial of Carraguard was unable to demonstrate a reduction in women's risk of HIV infection, which may have been due, in part, to low adherence (gel used in 42 % of vaginal sex acts, on average). A secondary analysis was undertaken to understand baseline factors associated with high adherence (gel used in aeyen85 % of sex acts). Women who reported aeyen1 vaginal sex act, returned aeyen1 opened applicator, and had aeyen1 conclusive post-enrollment HIV tes... VO - IS - SP - OP - KW - Microbicide; Carraguard; Adherence; Biomarker; Applicator test; Dye stain assay; South Africa; RANDOMIZED CONTROLLED-TRIAL; FEMALE SEX WORKERS; DYE STAIN ASSAY; HIV-INFECTION; VAGINAL GEL; PREEXPOSURE PROPHYLAXIS; CLINICAL-TRIALS; CONSISTENT USE; AFRICAN WOMEN; PREVENTION; 3142 Public health care science, environmental and occupational health; 3123 Gynaecology and paediatrics N1 - PP - ER -