TY  -  
T1  - Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor 
SN  -  /  
UR  - http://hdl.handle.net/10138/321187 
T3  -  
A1  - Fontana, Flavia; Fusciello, Manlio; Groeneveldt, Christianne; Capasso, Cristian; Chiaro, Jacopo; Feola, Sara; Liu, Zehua; Mäkilä, Ermei; Salonen, Jarno; Hirvonen, Jouni; Cerullo, Vincenzo; Santos, Hélder A. 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Recent approaches in the treatment of cancer focus on involving the immune system to control the tumor growth. The administration of immunotherapies, like checkpoint inhibitors, has shown impressive results in the long term survival of patients. Cancer vaccines are being investigated as further tools to prime tumor-specific immunity. Biomaterials show potential as adjuvants in the formulation of vaccines, and biomimetic elements derived from the membrane of tumor cells may widen the range of ant... 
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IS  -  
SP  -  
OP  -  
KW  - ACETALATED DEXTRAN; ANTIGEN; BLOCKADE; CANCER-IMMUNOTHERAPY; DELIVERY; EFFICACY; IMMUNE CELLS; NANOPARTICLES; SURFACE-CHEMISTRY; TUMOR-CELL VACCINE; biohybrid; cancer vaccine; cell membrane; melanoma; microfluidics; nanotechnology; immunotherapy; porous silicon; immune checkpoint inhibitor; 317 Pharmacy; 221 Nano-technology; 1182 Biochemistry, cell and molecular biology 
N1  -   
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ER  -