TY - T1 - Bistability breaks-off deterministic responses to intracortical stimulation during non-REM sleep SN - / UR - http://hdl.handle.net/10138/203730 T3 - A1 - Pigorini, Andrea; Sarasso, Simone; Proserpio, Paola; Szymanski, Caroline; Arnulfo, Gabriele; Casarotto, Silvia; Fecchio, Matteo; Rosanova, Mario; Mariotti, Maurizio; Lo Russo, Giorgio; Palva, J. Matias; Nobili, Lino; Massimini, Marcello A2 - PB - Y1 - 2015 LA - eng AB - During non-rapid eye movement (NREM) sleep (stage N3), when consciousness fades, cortico-cortical interactions are impaired while neurons are still active and reactive. Why is this? We compared cortico-cortical evoked-potentials recorded during wakefulness and NREM by means of time-frequency analysis and phase-locking measures in 8 epileptic patients undergoing intra-cerebral stimulations/recordings for clinical evaluation. We observed that, while during wakefulness electrical stimulation trigge... VO - IS - SP - OP - KW - Causality; Consciousness; Down-state; Intracranial; Phase-locking; EYE-MOVEMENT SLEEP; SLOW-WAVE SLEEP; CORTICAL EFFECTIVE CONNECTIVITY; NEOCORTICAL NEURONS; IN-VIVO; NETWORK MECHANISMS; LESS-THAN-1 HZ; BRAIN ACTIVITY; VISUAL-CORTEX; NREM SLEEP; 3112 Neurosciences N1 - PP - ER -