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T1  - CRY1 and CRY2 genetic variants in seasonality : A longitudinal and cross-sectional study 
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UR  - http://hdl.handle.net/10138/225830 
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A1  - Kovanen, Leena; Donner, Kati; Kaunisto, Mari; Partonen, Timo 
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Y1  - 2016 
LA  - eng 
AB  - Cryptochromes are key components of the circadian clocks that generate and maintain seasonal variations. The aim of our study was to analyze the associations of CRY1 and CRY2 genetic variants with the problematicity of seasonal variations, and whether the problematicity of seasonal variations changed during the follow-up of 11 years. Altogether 21 CRY1 and 16 CRY2 single-nucleotide polymorphisms (SNPs) were genotyped and analyzed in 5910 individuals from a Finnish nationwide population-based sam... 
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KW  - Behavior; Circadian; Cryptochrome; Diurnal; Genetic association; Mood; Population; MAMMALIAN CIRCADIAN CLOCK; BIPOLAR DISORDER; SUPRACHIASMATIC NUCLEUS; GLUCOSE-HOMEOSTASIS; INSULIN-RESISTANCE; MOOD DISORDERS; LARGE-SCALE; ASSOCIATION; CRYPTOCHROMES; DEPRESSION; 3124 Neurology and psychiatry; 3111 Biomedicine 
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