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T1  - Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: Re-analysis of randomized trial data 
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UR  - http://hdl.handle.net/10138/331770 
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A1  - Hemilä, Harri; Chalker, Elizabeth 
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Y1  - 2021 
LA  - eng 
AB  - In this individual patient data meta-analysis we examined datasets of two randomized placebo-controlled trials which investigated the effect of nasal carrageenan separately on children and adults. In both trials, iota-carrageenan was administered nasally three times per day for 7 days for patients with the common cold and follow-up lasted for 21 days. We used Cox regression to estimate the effect of carrageenan on recovery rate. We also used quantile regression to calculate the effect of carrage... 
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KW  - 317 Pharmacy; common cold; iota-carrageenan; meta-analysis; quantile treatment effect; randomized trial; rhinovirus; SARS-CoV-2; HERPES-SIMPLEX-VIRUS; COMMON COLD; ANTIVIRAL ACTIVITY; VITAMIN-C; POLYSACCHARIDES; LOZENGES 
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