TY  -  
T1  - Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells 
SN  -  /  
UR  - http://hdl.handle.net/10138/231799 
T3  -  
A1  - Borger, Jessica G.; Morrison, Vicky L.; Filby, Andrew; Garcia, Celine; Uotila, Liisa M.; Simbari, Fabio; Fagerholm, Susanna C.; Zamoyska, Rose 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - TCR stimulation by peptide-MHC complexes on APCs requires precise reorganization of molecules into the area of cellular contact to form an immunological synapse from where T cell signaling is initiated. Caveolin (Cav) 1, a widely expressed transmembrane protein, is involved in the regulation of membrane composition, cellular polarity and trafficking, and the organization of signal transduction pathways. The presence of Cav1 protein in T cells was identified only recently, and its function in thi... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - FUNCTION-ASSOCIATED MOLECULE-1; LYMPHOCYTE FUNCTION; PLASMA-MEMBRANE; IN-VIVO; IMMUNOLOGICAL SYNAPSE; LFA-1-DEFICIENT MICE; ACTIN CYTOSKELETON; LEUKOCYTE ADHESION; INTEGRIN FUNCTION; PHORBOL ESTER; 3121 General medicine, internal medicine and other clinical medicine 
N1  -   
PP  -  
ER  -