TY - T1 - Cell influx and contractile actomyosin force drive mammary bud growth and invagination SN - / UR - http://hdl.handle.net/10138/333258 T3 - A1 - Trela, Ewelina; Lan, Qiang; Myllymäki, Satu-Marja; Villeneuve, Clémentine; Lindström, Riitta; Kumar, Vinod; Wickström, Sara A.; Mikkola, Marja L. A2 - PB - Y1 - 2021 LA - eng AB - The mammary gland develops from the surface ectoderm during embryogenesis and proceeds through morphological phases defined as placode, hillock, bud, and bulb stages followed by branching morphogenesis. During this early morphogenesis, the mammary bud undergoes an invagination process where the thickened bud initially protrudes above the surface epithelium and then transforms to a bulb and sinks into the underlying mesenchyme. The signaling pathways regulating the early morphogenetic steps have ... VO - IS - SP - OP - KW - DIFFERENTIATION; LINE; MIGRATION; MORPHOGENESIS; MORPHOLOGY; MOUSE; POLARITY; PROLIFERATION; ROLES; SONIC-HEDGEHOG; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -