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T1  - Changes in energy metabolism, and levels of stress-related hormones and electrolytes in horses after intravenous administration of romifidine and the peripheral alpha-2 adrenoceptor antagonist vatinoxan 
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UR  - http://hdl.handle.net/10138/235380 
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A1  - Pakkanen, Soile Anja Eliisa; de Vries, Annemarie; Raekallio, Marja Riitta; Mykkänen, Anna Kristina; Palviainen, Mari Johanna; Sankari, Satu Marja; Vainio, Outi Maritta 
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Y1  - 2018 
LA  - eng 
AB  - Background: Romifidine, an alpha-2 adrenoceptor agonist, is a widely-used sedative in equine medicine. Besides the desired sedative and analgesic actions, alpha-2 adrenoceptor agonists have side effects like alterations of plasma concentrations of glucose and certain stress-related hormones and metabolites in various species. Vatinoxan (previously known as MK-467), in turn, is an antagonist of alpha-2 adrenoceptors. Because vatinoxan does not cross the blood brain barrier in significant amounts,... 
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KW  - alpha-2 adrenoceptor agonist; Glucose; Horse; Hyperglycaemia; Insulin; MK-467; Romifidine; Vatinoxan; CORTISOL CONCENTRATIONS; PHYSIOLOGICAL-RESPONSES; RECEPTOR ANTAGONIST; PLASMA-GLUCOSE; DOGS; MEDETOMIDINE; DETOMIDINE; DEXMEDETOMIDINE; ATIPAMEZOLE; 413 Veterinary science 
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