TY  -  
T1  - Chronic Alcohol Causes Alteration of Lipidome Profiling in Brain 
SN  -  /  
UR  - http://hdl.handle.net/10138/314746 
T3  -  
A1  - Wang, Liang; Li, Menglu; Bu, Qian; Li, Hongchun; Xu, Wei; Liu, Chunqi; Gu, Hui; Zhang, Jiamei; Wan, Xuemei; Zhao, Yinglan; Cen, Xiaobo 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Much efforts have been tried to clarify the molecular mechanism of alcohol-induced brain damage from the perspective of genome and protein; however, the effect of chronic alcohol exposure on global lipid profiling of brain is unclear. In the present study, by using Q-TOF/MS-based lipidomics approach, we investigated the comprehensive lipidome profiling of brain from the rats orally administrated with alcohol daily, continuously for one year. Through systematically analysis of all lipids in prefr... 
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IS  -  
SP  -  
OP  -  
KW  - 3111 Biomedicine; Alcohol abuse; Lipidome profiling; ER stress; HOMEOSTASIS; ACID; ALZHEIMERS-DISEASE; USE DISORDER; ENDOPLASMIC-RETICULUM STRESS; PROTECTS; METABOLISM; LIVER; BURDEN; CONSUMPTION 
N1  -   
PP  -  
ER  -