TY  -  
T1  - Circulating Liver-enriched Antimicrobial Peptide-2 Decreases During Male Puberty 
SN  -  /  
UR  - http://hdl.handle.net/10138/342227 
T3  -  
A1  - Varimo, Tero; Miettinen, Paivi J.; Vaaralahti, Kirsi; Toppari, Jorma; Huopio, Hanna; Voutilainen, Raimo; Tenhola, Sirpa; Hero, Matti; Raivio, Taneli 
A2  -  
PB  -  
Y1  - 2022 
LA  - eng 
AB  - Context: Circulating levels of liver-enriched antimicrobial peptide 2 (LEAP2), a ghrelin receptor antagonist, decrease under caloric restriction and increase in obesity. The role of LEAP2 in male puberty, a phase with accelerated energy demand, is unclear. Objective: This work aimed to investigate whether circulating LEAP2 levels are downregulated in boys following the onset of puberty to respond to the energy need required for growth. Methods: We determined circulating LEAP2 levels in 28 boys w... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - liver-enriched antimicrobial peptide-2; acylated ghrelin; puberty; testosterone; SECRETAGOGUE RECEPTOR; CONSTITUTIONAL DELAY; BODY-COMPOSITION; GROWTH; GHRELIN; ANTAGONIST; RESISTANCE; LEAP2; BOYS; GENE; 3123 Gynaecology and paediatrics 
N1  -   
PP  -  
ER  -