TY - T1 - Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis SN - / UR - http://hdl.handle.net/10138/334421 T3 - A1 - Bossen, Lars; Vesterhus, Mette; Hov, Johannes R.; Färkkilä, Martti; Rosenberg, William M.; Moller, Holger J.; Boberg, Kirsten M.; Karlsen, Tom H.; Gronbaek, Henning A2 - PB - Y1 - 2021 LA - eng AB - INTRODUCTION: Primary sclerosing cholangitis (PSC) is a progressive liver disease characterized by bile duct inflammation and fibrosis. The role of macrophages in PSC development and progression is less studied. Macrophage activation markers soluble (s)CD163 and mannose receptor (sMR) are associated with disease severity and outcome in other liver diseases, but not previously investigated in PSC. We evaluated sCD163 and sMR regarding disease severity and prognosis in patients with PSC. METHODS: ... VO - IS - SP - OP - KW - SURROGATE END-POINTS; SOLUBLE CD163; PORTAL-HYPERTENSION; MANNOSE RECEPTOR; HEPATITIS-B; LIVER; FIBROSIS; MANAGEMENT; DISEASE; SCD163; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -