TY  -  
T1  - Combining CDKN1A gene expression and genome-wide SNPs in a twin cohort to gain insight into the heritability of individual radiosensitivity 
SN  -  /  
UR  - http://hdl.handle.net/10138/308427 
T3  -  
A1  - Zyla, Joanna; Kabacik, Sylwia; O'Brien, Grainne; Wakil, Salma; Al-Harbi, Najla; Kaprio, Jaakko; Badie, Christophe; Polanska, Joanna; Alsbeih, Ghazi 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Individual variability in response to radiation exposure is recognised and has often been reported as important in treatment planning. Despite many efforts to identify biomarkers allowing the identification of radiation sensitive patients, it is not yet possible to distinguish them with certainty before the beginning of the radiotherapy treatment. A comprehensive analysis of genome-wide single-nucleotide polymorphisms (SNPs) and a transcriptional response to ionising radiation exposure in twins ... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Radiation response; CDKN1A; p value integration; Twin study; GWAS; DOUBLE-STRAND BREAKS; SIB-PAIR ANALYSIS; IONIZING-RADIATION; P-VALUES; ASSOCIATION; CANCER; REPAIR; IDENTIFICATION; METAANALYSIS; LYMPHOCYTES; 1184 Genetics, developmental biology, physiology 
N1  -   
PP  -  
ER  -