TY  -  
T1  - Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component signaling 
SN  -  /  
UR  - http://hdl.handle.net/10138/334399 
T3  -  
A1  - Multamäki, Elina; Nanekar, Rahul; Morozov, Dmitry; Lievonen, Topias; Golonka, David; Wahlgren, Weixiao Yuan; Stucki-Buchli, Brigitte; Rossi, Jari; Hytönen, Vesa P.; Westenhoff, Sebastian; Ihalainen, Janne A.; Möglich, Andreas; Takala, Heikki 
A2  -  
PB  -  
Y1  - 2021 
LA  - eng 
AB  - Bacterial phytochrome photoreceptors usually belong to two-component signaling systems which transmit environmental stimuli to a response regulator through a histidine kinase domain. Phytochromes switch between red light-absorbing and far-red light-absorbing states. Despite exhibiting extensive structural responses during this transition, the model bacteriophytochrome from Deinococcus radiodurans (DrBphP) lacks detectable kinase activity. Here, we resolve this long-standing conundrum by comparat... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - CYANOBACTERIAL PHYTOCHROME CPH1; HISTIDINE KINASES; AGROBACTERIUM-TUMEFACIENS; CRYSTAL-STRUCTURE; TRANSDUCTION; PROTEINS; INSIGHTS; PHOSPHORYLATION; REARRANGEMENTS; ACTIVATION; 3111 Biomedicine 
N1  -   
PP  -  
ER  -