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T1  - Comparative efficacy and complication rates after local treatment for cervical intraepithelial neoplasia and stage 1a1 cervical cancer : protocol for a systematic review and network meta-analysis from the CIRCLE Group 
SN  -  /  
UR  - http://hdl.handle.net/10138/309745 
T3  -  
A1  - Athanasiou, Antonios; Veroniki, Areti Angeliki; Efthimiou, Orestis; Kalliala, Ilkka; Naci, Huseyin; Bowden, Sarah; Paraskevaidi, Maria; Martin-Hirsch, Pierre; Bennett, Philip; Paraskevaidis, Evangelos; Salanti, Georgia; Kyrgiou, Maria 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Introduction Local treatments for cervical intraepithelial neoplasia (CIN) and microinvasive disease remove or ablate a cone-shaped part of the uterine cervix containing the abnormal cells. A trend toward less radical techniques has raised concerns that this may adversely impact the rates of precancerous and cancerous recurrence. However, there has been no strong evidence to support such claims. We hereby describe a protocol of a systematic review and network meta-analysis that will update the e... 
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KW  - Cervical intraepithelial neoplasia; therapy; Treatment outcome; Recurrence; Conization; adverse effects; Ablation techniques; LOOP ELECTROSURGICAL EXCISION; MULTIPLE-TREATMENTS; HETEROGENEITY; INCONSISTENCY; PROPORTION; LESIONS; TRIALS; EXTENT; RISK; 3121 General medicine, internal medicine and other clinical medicine 
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ER  -