TY - T1 - Comparative interactomes of HSF1 in stress and disease reveal a role for CTCF in HSF1-mediated gene regulation SN - / UR - http://hdl.handle.net/10138/341310 T3 - A1 - Burchfiel, Eileen T.; Vihervaara, Anniina; Guertin, Michael J.; Gomez-Pastor, Rocio; Thiele, Dennis J. A2 - PB - Y1 - 2021 LA - eng AB - Heat shock transcription factor 1 (HSF1) orchestrates cellular stress protection by activating or repressing gene transcription in response to protein misfolding, oncogenic cell proliferation, and other environmental stresses. HSF1 is tightly regulated via intramolecular repressive interactions, post-ranslational modifications, and protein-protein interactions. How these HSF1 regulatory protein interactions are altered in response to acute and chronic stress is largely unknown. To elucidate the ... VO - IS - SP - OP - KW - 1182 Biochemistry, cell and molecular biology N1 - PP - ER -