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T1  - Compared to casein, bovine lactoferrin reduces plasma leptin and corticosterone and affects hypothalamic gene expression without altering weight gain or fat mass in high fat diet fed C57/BL6J mice 
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UR  - http://hdl.handle.net/10138/162329 
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A1  - McManus, Bettina; Korpela, Riitta; O'Connor, Paula; Schellekens, Harriet; Cryan, John F.; Cotter, Paul D.; Nilaweera, Kanishka N. 
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Y1  - 2015 
LA  - eng 
AB  - Background: Several studies in both humans and rodents have examined the use of lactoferrin as a dietary solution to weight gain and visceral fat accretion and have shown promising results in the short term (up to 7 weeks). This study examined the effects of giving lactoferrin over a longer period of time. Methods: For 13 weeks, male C57/BL6J mice were given a diet containing 10 % kJ fat and 20 % kJ casein (LFD) or a diet with 45 % kJ fat and either 20 % kJ casein (HFD) or 20 % kJ lactoferrin (H... 
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KW  - Lactoferrin; High fat diet; Weight gain; Fat mass; Obesity; Hypothalamus; Microarray; Leptin; Corticosterone; PITUITARY-ADRENAL AXIS; ENERGY-BALANCE; UP-REGULATION; POMC NEURONS; RATS; RESTRICTION; ADIPOCYTES; METABOLISM; INSULIN; OBESITY; 3111 Biomedicine 
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