TY  -  
T1  - Complement Component C3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma 
SN  -  /  
UR  - http://hdl.handle.net/10138/189042 
T3  -  
A1  - Riihila, Pilvi; Nissinen, Liisa; Farshchian, Mehdi; Kallajoki, Markku; Kivisaari, Atte; Meri, Seppo; Grenman, Reidar; Peltonen, Sirkku; Peltonen, Juha; Pihlajaniemi, Taina; Heljasvaara, Ritva; Kahari, Veli-Matti 
A2  -  
PB  -  
Y1  - 2017 
LA  - eng 
AB  - Cutaneous squamous cell carcinoma (cSCC) is one of the most common metastatic skin cancers with increasing incidence. We examined the roles of complement component C3 and complement factor B (CFB) in the growth of cSCC. Analysis of cSCC cell lines (n = 8) and normal human epidermal kerati-nocytes (n = 11) with real-time quantitative PCR and Western blotting revealed up-regulation of C3 and CFB expression in cSCC cells. Immunohistochemical staining revealed stronger tumor cell specific Labeling f... 
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IS  -  
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OP  -  
KW  - HUMAN KERATINOCYTES; TUMOR MICROENVIRONMENT; ALTERNATIVE PATHWAY; LUNG-CANCER; FACTOR-I; FACTOR-H; EXPRESSION; PROGRESSION; SKIN; ACTIVATION; 3111 Biomedicine 
N1  -   
PP  -  
ER  -