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T1  - Complement in malaria : immune evasion strategies and role in protective immunity 
SN  -  /  
UR  - http://hdl.handle.net/10138/314450 
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A1  - Kiyuka, Patience Kerubo; Meri, Seppo; Khattab, Ayman 
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PB  -  
Y1  - 2020 
LA  - eng 
AB  - The malaria parasite has for long been thought to escape host complement attack as a survival strategy. However, it was only recently that complement evasion mechanisms of the parasite were described. Simultaneously, the role of complement in antibody-mediated naturally acquired and vaccine-induced protection against malaria has also been reported. Such findings should be considered in future vaccine design, given the current need to develop more efficacious vaccines against malaria. Parasite an... 
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KW  - complement; immunity; malaria; Plasmodium; NATURALLY ACQUIRED ANTIBODIES; BLOOD-CELL INVASION; PLASMODIUM-FALCIPARUM; FACTOR-H; MONOCLONAL-ANTIBODIES; ANTIGENIC VARIATION; SURFACE PROTEIN; MEDIATED LYSIS; TRANSMISSION; VACCINE; 3111 Biomedicine; 1182 Biochemistry, cell and molecular biology 
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