TY  -  
T1  - Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic beta-oxidation trifunctional enzyme complexes 
SN  -  /  
UR  - http://hdl.handle.net/10138/317733 
T3  -  
A1  - Sah-Teli, Shiv K.; Hynönen, Mikko J.; Schmitz, Werner; Geraets, James A.; Seitsonen, Jani; Pedersen, Jan Skov; Butcher, Sarah J.; Wierenga, Rik K.; Venkatesan, Rajaram 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - The trifunctional enzyme (TFE) catalyzes the last three steps of the fatty acid beta-oxidation cycle. Two TFEs are present in Escherichia coli, EcTFE and anEcTFE. EcTFE is expressed only under aerobic conditions, whereas anEcTFE is expressed also under anaerobic conditions, with nitrate or fumarate as the ultimate electron acceptor. The anEcTFE subunits have higher sequence identity with the human mitochondrial TFE (HsTFE) than with the soluble EcTFE. Like HsTFE, here it is found that anEcTFE is... 
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IS  -  
SP  -  
OP  -  
KW  - FATTY-ACID OXIDATION; ENOYL-COA HYDRATASE; CRYSTAL-STRUCTURE; MULTIENZYME COMPLEX; SOLUTION SCATTERING; STRUCTURAL BASIS; BIOLOGICAL MACROMOLECULES; INTERMEDIATE; BINDING; PURIFICATION; 1182 Biochemistry, cell and molecular biology 
N1  -   
PP  -  
ER  -