TY - T1 - Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles SN - / UR - http://hdl.handle.net/10138/304243 T3 - A1 - Clayton, Aled; Boilard, Eric; Buzas, Edit I; Cheng, Lesley; Falcón-Perez, Juan Manual; Gardiner, Chris; Gustafson, Dakota; Gualerzi, Alice; Hendrix, An; Hoffman, Andrew; Jones, Jennifer; Lässer, Cecilia; Lawson, Charlotte; Lenassi, Metka; Nazarenko, Irina; O’Driscoll, Lorraine; Pink, Ryan; Siljander, Pia R-M; Soekmadji, Carolina; Wauben, Marca; Welsh, Joshua A; Witwer, Ken; Zheng, Lei; Nieuwland, Rienk A2 - PB - Y1 - 2019 LA - eng AB - There is an increasing interest in exploring clinically relevant information that is present in body fluids, and extracellular vesicles (EVs) are intrinsic components of body fluids (?liquid biopsies?). In this report, we will focus on blood. Blood contains not only EVs but also cells, and non-EV particles including lipoproteins. Due to the high concentration of soluble proteins and lipoproteins, blood, plasma and serum have a high viscosity and density, which hampers the concentration, isolatio... VO - IS - SP - OP - KW - Exosomes; SOCIETY; STANDARDIZATION; biomarker; blood; extracellular vesicle; microvesicles; plasma; pre-analytical variables; serum; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -