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T1  - Contrasting microbiotas between Finnish and Estonian infants : exposure to Acinetobacter may contribute to the allergy gap 
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UR  - http://hdl.handle.net/10138/327210 
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A1  - Ruokolainen, Lasse; Parkkola, Anna; Karkman, Antti; Sinkko, Hanna; Peet, Aleksandr; Hämäläinen, Anu-Maaria; von Hertzen, Leena; Tillmann, Vallo; Koski, Katriina; Virtanen, Suvi M.; Niemelä, Onni; Haahtela, Tari; Knip, Mikael 
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Y1  - 2020 
LA  - eng 
AB  - Background Allergic diseases are more common in Finland than in Estonia, which-according to the biodiversity hypothesis-could relate to differences in early microbial exposures. Methods We aimed at defining possible microbial perturbations preceding early atopic sensitization. Stool, nasal and skin samples of 6-month-old DIABIMMUNE study participants with HLA susceptibility to type 1 diabetes were collected. We compared microbiotas of sensitized (determined by specific IgE results at 18 months o... 
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KW  - 3111 Biomedicine; atopic sensitisation; IgE; intestine; microbiota; respiratory; skin; EARLY-LIFE; atopic sensitization; RISK; PREVALENCE; ENVIRONMENTAL BIODIVERSITY; DISPARITIES; DISEASE; ASTHMA; DIVERSITY; SKIN; ATOPIC SENSITIZATION 
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