TY - T1 - Convergent evolution of [D-Leucine(1)] microcystin-LR in taxonomically disparate cyanobacteria SN - / UR - http://hdl.handle.net/10138/313669 T3 - A1 - Shishido, Tania Keiko; Kaasalainen, Ulla; Fewer, David Peter; Rouhiainen, Leo A O; Jokela, Jouni; Wahlsten, Matti; Fiore, Marli Fátima; Yunes, João Sarkis; Rikkinen, Jouko; Sivonen, Kaarina A2 - PB - Y1 - 2013 LA - eng AB - BACKGROUND: Many important toxins and antibiotics are produced by non-ribosomal biosynthetic pathways. Microcystins are a chemically diverse family of potent peptide toxins and the end-products of a hybrid NRPS and PKS secondary metabolic pathway. They are produced by a variety of cyanobacteria and are responsible for the poisoning of humans as well as the deaths of wild and domestic animals around the world. The chemical diversity of the microcystin family is attributed to a number of genetic e... VO - IS - SP - OP - KW - 1183 Plant biology, microbiology, virology; 1184 Genetics, developmental biology, physiology N1 - PP - ER -