TY  -  
T1  - Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis 
SN  -  /  
UR  - http://hdl.handle.net/10138/234198 
T3  -  
A1  - Boku, Shuken; Takeshi, Izumi; Abe, Seiji; Takahashi, Tomohisa; Nishi, Akira; Nomaru, Hiroko; Naka, Yasuhiko; Kang, Gina; Nagashima, Masako; Hishimoto, Akitoyo; Hishimoto, Akitoyo; Enomoto, Shingo; Duran Torres, Gilberto; Tanigaki, Kenji; Zhang, Jinghang; Ye, Kenny; Kato, Shigeki; Männistö, Pekka Topias; Kobayashi, Kazuto; Hiroi, Noboru 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Working memory capacity, a critical component of executive function, expands developmentally from childhood through adulthood. Anomalies in this developmental process are seen in individuals with autism spectrum disorder (ASD), schizophrenia and intellectual disabilities (ID), implicating this atypical process in the trajectory of developmental neuropsychiatric disorders. However, the cellular and neuronal substrates underlying this process are not understood. Duplication and triplication of cop... 
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KW  - 3112 Neurosciences; COMT; COMT gene duplication; CATECHOL-O-METHYLTRANSFERASE; AUTISM SPECTRUM DISORDER; INTELLECTUAL DISABILITY; DUPLICATION SYNDROME; COGNITIVE DEFICITS; EXECUTIVE FUNCTION; SCHIZOPHRENIA; PROLIFERATION; INTELLIGENCE; CHILDHOOD 
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ER  -