TY  -  
T1  - Cord-Blood Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes 
SN  -  /  
UR  - http://hdl.handle.net/10138/299988 
T3  -  
A1  - Lamichhane, Santosh; Ahonen, Linda; Dyrlund, Thomas Sparholt; Dickens, Alex M.; Siljander, Heli; Hyöty, Heikki; Ilonen, Jorma; Toppari, Jorma; Veijola, Riitta; Hyötyläinen, Tuulia; Knip, Mikael; Oresic, Matej 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - Previous studies suggest that children who progress to type 1 diabetes (T1D) later in life already have an altered serum lipid molecular profile at birth. Here, we compared cord blood lipidome across the three study groups: children who progressed to T1D (PT1D; n = 30), children who developed at least one islet autoantibody but did not progress to T1D during the follow-up (P1Ab; n = 33), and their age-matched controls (CTR; n = 38). We found that phospholipids, specifically sphingomyelins, were ... 
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KW  - type 1 diabetes; cord blood; lipidomics; metabolomics; autoimmunity; METABOLISM; PHOSPHATIDYLCHOLINE; DISCOVERY; 3111 Biomedicine; 3121 General medicine, internal medicine and other clinical medicine 
N1  -   
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ER  -