TY  -  
T1  - Cumulative use of salivary markers with an adaptive design improves detection of periodontal disease over fixed biomarker thresholds 
SN  -  /  
UR  - http://hdl.handle.net/10138/305973 
T3  -  
A1  - Gursoy, Ulvi Kahraman; Pussinen, Pirkko J.; Salomaa, Veikko; Syrjalainen, Sanna; Kononen, Eija 
A2  -  
PB  -  
Y1  - 2018 
LA  - eng 
AB  - Objective: Aim was to analyze the diagnostic ability of cumulative risk score (CRS), which uses salivary levels of Porphyromonas gingivalis, interleukin (IL)-1 beta, and matrix metalloproteinase (MMP)-8 in an adaptive design, compared to previously reported thresholds of each marker alone. Materials and Methods: Oral and general health information of 463 participants were included in the analysis. Having the percentage of bleeding on probing (BOP) > 25%, having at least two sites with probing po... 
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IS  -  
SP  -  
OP  -  
KW  - Biomarker; interleukin-1 beta; matrix metalloproteinase-8; periodontitis; porphyromonas gingivalis; saliva; MATRIX METALLOPROTEINASES; HOST; 313 Dentistry 
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ER  -