TY - T1 - Cyanobacteria as a Source for Novel Anti-Leukemic Compounds SN - / UR - http://hdl.handle.net/10138/307572 T3 - A1 - Humisto, Anu; Herfindal, Lars; Jokela, Jouni; Karkman, Antti; Bjørnstad, Ronja; Choudhury, Romi R.; Sivonen, Kaarina A2 - PB - Y1 - 2015 LA - eng AB - Cyanobacteria are an inspiring source of bioactive secondary metabolites. These bioactive agents are a diverse group of compounds which are varying in their bioactive targets, the mechanisms of action, and chemical structures. Cyanobacteria from various environments, especially marine benthic cyanobacteria, are found to be rich sources for the search for novel bioactive compounds. Several compounds with anticancer activities have been discovered from cyanobacteria and some of these have succeede... VO - IS - SP - OP - KW - Apoptosis; acute myeloid leukemia; Baltic Sea; bioactive compounds; cyanobacteria; hepatocyte; Molm13; IPC-81; HISTONE DEACETYLASE INHIBITOR; MARINE CYANOBACTERIUM; LYNGBYA-MAJUSCULA; NATURAL-PRODUCTS; BIOLOGICAL EVALUATION; ANTICANCER AGENTS; DRUG DISCOVERY; LEUKEMIA-CELLS; SYMPLOCA SP; POTENT; 1182 Biochemistry, cell and molecular biology; 1183 Plant biology, microbiology, virology; 317 Pharmacy N1 - PP - ER -