TY - T1 - DNA methylation pathway associated with insufficient sleep SN - / UR - URN:NBN:fi:hulib-201811153537; http://hdl.handle.net/10138/278381 T3 - A1 - Lahtinen, Alexandra A2 - PB - Helsingin yliopisto Y1 - 2018 LA - eng AB - The need to sleep is physiologically regulated and lack of sleep results in impaired daily performance and feeling of tiredness. If sleep disturbance persists for a long time, the risk of many somatic and mental disorders increases. The study of the key molecular processes triggered by insufficient sleep could foster the assessment and enhance the methods of prevention and cure of these long-term health risks. Both insufficient and mistimed sleep have been shown to strongly affect cell transcri... VO - IS - SP - OP - KW - insufficient sleep; DNA methylation; shift work disorder; pathway analysis; epigenome-wide association study N1 - PP - ER -