TY  -  
T1  - Defining the Design Principles of Skin Epidermis Postnatal Growth 
SN  -  /  
UR  - http://hdl.handle.net/10138/315806 
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A1  - Dekoninck, Sophie; Hannezo, Edouard; Sifrim, Alejandro; Miroshnikova, Yekaterina A.; Aragona, Mariaceleste; Malfait, Milan; Gargouri, Souhir; de Neunheuser, Charlotte; Dubois, Christine; Voet, Thierry; Wickström, Sara A.; Simons, Benjamin D.; Blanpain, Cédric 
A2  -  
PB  -  
Y1  - 2020 
LA  - eng 
AB  - Summary During embryonic and postnatal development, organs and tissues grow steadily to achieve their final size at the end of puberty. However, little is known about the cellular dynamics that mediate postnatal growth. By combining in vivo clonal lineage tracing, proliferation kinetics, single-cell transcriptomics, and in vitro micro-pattern experiments, we resolved the cellular dynamics taking place during postnatal skin epidermis expansion. Our data revealed that harmonious growth is engineer... 
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KW  - 1184 Genetics, developmental biology, physiology; stem cells; epidermis; postnatal; growth; development; self-renewal; skin; progenitors; imbalance; differentiation; STEM-CELLS; INTERFOLLICULAR EPIDERMIS; PATTERNS; TENSION; PROLIFERATION; GENE-EXPRESSION; DYNAMICS; FORCES; DIFFERENTIATION 
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