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T1  - Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD - A Systematic Review 
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UR  - http://hdl.handle.net/10138/165225 
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A1  - Petäjä, Elina M.; Yki-Järvinen, Hannele 
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Y1  - 2016 
LA  - eng 
AB  - Non-alcoholic fatty liver disease (NAFLD) covers a spectrum of disease ranging from simple steatosis (NAFL) to non-alcoholic steatohepatitis (NASH) and fibrosis. "Obese/Metabolic NAFLD" is closely associated with obesity and insulin resistance and therefore predisposes to type 2 diabetes and cardiovascular disease. NAFLD can also be caused by common genetic variants, the patatin-like phospholipase domain-containing 3 (PNPLA3) or the transmembrane 6 superfamily member 2 (TM6SF2). Since NAFL, irre... 
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KW  - insulin resistance; liver fat; obesity; PNPLA3; TM6SF2; MAGNETIC-RESONANCE-SPECTROSCOPY; MORBIDLY OBESE-PATIENTS; HEPATIC STEATOSIS; COMPUTED-TOMOGRAPHY; I148M VARIANT; CONFERS SUSCEPTIBILITY; CARDIOVASCULAR-DISEASE; TRIGLYCERIDE CONTENT; DIAGNOSTIC-ACCURACY; METABOLIC SYNDROME; 3121 General medicine, internal medicine and other clinical medicine 
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