TY  -  
T1  - Dereplication of Natural Products with Antimicrobial and Anticancer Activity from Brazilian Cyanobacteria 
SN  -  /  
UR  - http://hdl.handle.net/10138/317362 
T3  -  
A1  - Shishido, Tania Keiko; Popin, Rafael Vicentini; Jokela, Jouni; Wahlsten, Matti; Fiore, Marli Fatima; Fewer, David P.; Herfindal, Lars; Sivonen, Kaarina 
A2  -  
PB  -  
Y1  - 2020 
LA  - eng 
AB  - Cyanobacteria are photosynthetic organisms that produce a large diversity of natural products with interesting bioactivities for biotechnological and pharmaceutical applications. Cyanobacterial extracts exhibit toxicity towards other microorganisms and cancer cells and, therefore, represent a source of potentially novel natural products for drug discovery. We tested 62 cyanobacterial strains isolated from various Brazilian biomes for antileukemic and antimicrobial activities. Extracts from 39 st... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - natural products; mass spectrometry; leukemia; antifungal; antibacterial; cyanotoxins; Nostoc; MARINE CYANOBACTERIA; GEN. NOV; MOLECULAR-MECHANISMS; COMPARATIVE GENOMICS; PROTEASE INHIBITORS; MASS-SPECTROMETRY; CYCLIC PEPTIDE; CELL-LINES; DIVERSITY; APOPTOSIS; 11832 Microbiology and virology 
N1  -   
PP  -  
ER  -