TY - T1 - Development of a modified Vaccinia virus expressing an immunostimulatory molecule SN - / UR - URN:NBN:fi:hulib-202104011790; http://hdl.handle.net/10138/328666 T3 - A1 - Juntunen, Maiju A2 - PB - Helsingin yliopisto Y1 - 2020 LA - eng AB - Cancer immunotherapy refers to therapy strategies that utilise the mechanisms of the immune system to treat cancer patients. The benefits of the approach include the possibility for specific targeting and utilisation of the host immune system. The treatment methods include cancer vaccines, oncolytic viruses (OVs), cell-based immunotherapies and antibodies. The interplay between the cancer and the immune system has been observed crucial for the progress of the cancer and the success of immunother... VO - IS - SP - OP - KW - cancer; immunotherapy; immunovirotherapy; oncolytic virus; vaccinia virus; STING; stimulator of interferon genes; Biofarmasia; Biopharmaceutics; Biofarmaci; Lääketutkimuksen, farmaseuttisen tuotekehityksen ja lääkitysturvallisuuden maisteriohjelma; Master’s Programme in Pharmaceutical Research, Development and Safety; Magisterprogrammet i farmaceutisk forskning, utveckling och säkerhet N1 - PP - ER -