TY  -  
T1  - Diagnostic and prognostic role of expressed KRAS and BRAF mutations in MAPK/ERK-driven cancers 
SN  -  /  
UR  - URN:ISBN:978-951-51-7369-0; http://hdl.handle.net/10138/330388 
T3  -  
A1  - Dang, Kien 
A2  -  
PB  - Helsingin yliopisto 
Y1  - 2021 
LA  - en 
AB  - The aim of this doctoral thesis was to utilize molecular biology techniques to detect expressed KRAS and BRAF mutations in samples at high sensitivity and specificity and evaluate the clinical role of the RNA expression of these mutations in certain MAPK/ERK-driven cancers.

In the early phase of the study, we developed a novel method named extendable blocking probe reverse transcription (ExBP-RT) for detecting expressed mutations at the mRNA level. With this method we were able to detect mutatio... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - clinical Chemistry 
N1  -   
PP  -  
ER  -