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T1  - Differential metabolomic signatures of declining renal function in Types 1 and 2 diabetes 
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UR  - http://hdl.handle.net/10138/340442 
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A1  - Manca, Maria Laura; Solini, Anna; Haukka, Jani K.; Sandholm, Niina; Forsblom, Carol; Groop, Per Henrik; Ferrannini, Ele 
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Y1  - 2021 
LA  - eng 
AB  - Background: Chronic kidney disease (CKD) shows different clinical features in Types1 (T1D) and 2 diabetes (T2D). Metabolomics have recently provided useful contribution to the identification of biomarkers of CKD progression in either form of the disease. However, no studies have so far compared plasma metabolomics between T1D and T2D in order to identify differential signatures of progression of estimated glomerular filtration rate (eGFR) decline. Methods: We used two large cohorts of T1D (from ... 
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KW  - 3121 General medicine, internal medicine and other clinical medicine; GFR; metabolomics; nephropathy; Type 1 diabetes; Type 2 diabetes; METABOLITES; MAST-CELLS; RISK; NEPHROPATHY; SERUM URIC-ACID; INDIVIDUALS; PLASMA; DYSFUNCTION; CHRONIC KIDNEY-DISEASE; ASSOCIATION 
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