TY - T1 - Does securin expression have significance in prognostication of oral tongue cancer? A pilot study SN - / UR - http://hdl.handle.net/10138/228575 T3 - A1 - Heikkinen, Ilkka; Almangush, Alhadi; Hagström, Jaana; Bello, Ibrahim O.; Kauppila, Joonas H.; Mäkinen, Laura; Haglund, Caj; Nieminen, Pentti; Salo, Tuula; Leivo, Ilmo A2 - PB - Y1 - 2016 LA - eng AB - The proliferation marker, securin, is involved in the progression of many carcinomas. However, its expression in oral tongue squamous cell carcinoma (OTSCC) has not been previously studied. We examined securin expression by immunohistochemistry in OTSCC. A total of 93 cases treated for OTSCC were included in this study. Expression of securin in OTSCC was studied by immunohistochemistry of tissue microarrays (52 cases) and routine tumor sections (41 cases). Securin overexpression is significantly... VO - IS - SP - OP - KW - Oral tongue squamous cell carcinoma; Prognosis; Securin; Expression; SQUAMOUS-CELL CARCINOMA; TUMOR TRANSFORMING GENE; BREAST-CANCER; POOR-PROGNOSIS; OVEREXPRESSION; SURVIVAL; PTTG1; ANEUPLOIDY; APOPTOSIS; CDC20; 3125 Otorhinolaryngology, ophthalmology N1 - PP - ER -