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T1  - Does telomere length predict decline in physical functioning in older twin sisters during an 11-year follow-up? 
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UR  - http://hdl.handle.net/10138/223914 
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A1  - Sillanpaa, Elina; Tormakangas, Timo; Rantanen, Taina; Kaprio, Jaakko; Sipila, Sarianna 
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Y1  - 2016 
LA  - eng 
AB  - Leukocyte telomere length (LTL) is known to be associated with mortality, but its association with age-related decline in physical functioning and the development of disability is less clear. This study examined the associations between LTL and physical functioning, and investigated whether LTL predicts level of physical functioning over an 11-year follow-up. Older mono-(MZ) and dizygotic (DZ) twin sisters (n = 386) participated in the study. Relative LTL was measured by qPCR at baseline. Physic... 
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KW  - Telomere; Twin study; Physical functioning; Six-minute walking test; Physical activity; Biological aging; Missing data not at random; MAXIMAL WALKING SPEED; CARDIOVASCULAR-DISEASE; ENVIRONMENTAL-FACTORS; DANISH TWINS; HERITABILITY; ASSOCIATION; WOMEN; AGE; MORTALITY; METAANALYSIS; 3142 Public health care science, environmental and occupational health; 3121 General medicine, internal medicine and other clinical medicine 
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