TY - T1 - Dopamiinitransportteri (kirjallisuuskatsaus) : GDNF:n merkitys addiktiossa : amfetamiinin vaikutus striatumin dopamiinipitoisuuteen MEN2B- ja GDNF-cKO-hiirikannoilla (kokeellinen osa) SN - / UR - URN:NBN:fi-fe201801151211; http://hdl.handle.net/10138/38456 T3 - A1 - Montonen, Heidi A2 - PB - Helsingfors universitet Y1 - 2013 LA - fin AB - Literature review: The plasma membrane DA transporter (DAT) belongs to the family of Na+/Cl􀃭 dependent neurotransmitter transporters. DAT is the primary mechanism for clearance of dopamine from the extracellular space and transporting it back to the presynaptic nerve terminals. There's a great interest in the DAT and its regulation as its substrate, dopamine, mediates a wide array of physiological functions e.g. locomotor activity, cognition and the control of motivated behaviors. With select... VO - IS - SP - OP - KW - GDNF; MEN2B; Ret; dopamine transporter; amphetamine; microdialysis; neurotransmission; dopamine; amfetamiini; mikrodialyysi; neurotransmissio; dopamiini; dopamiinitransportteri; Farmakologi; Pharmacology; Farmakologia N1 - PP - ER -