TY  -  
T1  - Dual-trap optical tweezers with real-time force clamp control 
SN  -  / 0034-6748 
UR  - http://hdl.handle.net/10138/27789 
T3  -  
A1  - Wallin, Anders; Ojala, Heikki Viljami; Ziedaite, Gabija; Haeggström, Edward 
A2  -  
PB  -  
Y1  - 2011 
LA  - eng 
AB  - Single molecule force clamp experiments are widely used to investigate how enzymes, molecular motors, and other molecular mechanisms work. We developed a dual-trap optical tweezers instrument with real-time (200 kHz update rate) force clamp control that can exert 0–100 pN forces on trapped beads. A model for force clamp experiments in the dumbbell-geometry is presented. We observe good agreement between predicted and observed power spectra of bead position and force fluctuations. The model can b... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - 114 Physical sciences 
N1  -   
PP  -  
ER  -