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T1  - E-Science technologies in a workflow for personalized medicine using cancer screening as a case study 
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UR  - http://hdl.handle.net/10138/224483 
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A1  - Spjuth, Ola; Karlsson, Andreas; Clements, Mark; Humphreys, Keith; Ivansson, Emma; Dowling, Jim; Eklund, Martin; Jauhiainen, Alexandra; Czene, Kamila; Gronberg, Henrik; Sparen, Par; Wiklund, Fredrik; Cheddad, Abbas; Palsdottir, Porgerodur; Rantalainen, Mattias; Abrahamsson, Linda; Laure, Erwin; Litton, Jan-Eric; Palmgren, Juni 
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Y1  - 2017 
LA  - eng 
AB  - Objective: We provide an e-Science perspective on the workflow from risk factor discovery and classification of disease to evaluation of personalized intervention programs. As case studies, we use personalized prostate and breast cancer screenings. Materials and Methods: We describe an e-Science initiative in Sweden, e-Science for Cancer Prevention and Control (eCPC), which supports biomarker discovery and offers decision support for personalized intervention strategies. The generic eCPC contrib... 
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KW  - e-Science; cancer; personalized screening; data integration; modeling; simulation; BREAST-CANCER; MAMMOGRAPHIC DENSITY; PROSTATE-CANCER; HEALTH REGISTRIES; TUMOR-GROWTH; RISK; ASSOCIATION; BIOMARKERS; BENEFITS; THERAPY; 113 Computer and information sciences; 3122 Cancers; 3111 Biomedicine 
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