TY - T1 - Early discharge and home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban : an international multicentre single-arm clinical trial SN - / UR - http://hdl.handle.net/10138/314238 T3 - A1 - HoT-PE Investigators; Barco, Stefano; Schmidtmann, Irene; Ageno, Walter; Harjola, Veli-Pekka; Lankeit, Mareike A2 - PB - Y1 - 2020 LA - eng AB - Aims To investigate the efficacy and safety of early transition from hospital to ambulatory treatment in low-risk acute PE, using the oral factor Xa inhibitor rivaroxaban. Methods and results We conducted a prospective multicentre single-arm investigator initiated and academically sponsored management trial in patients with acute low-risk PE (EudraCT Identifier 2013-001657-28). Eligibility criteria included absence of (i) haemodynamic instability, (ii) right ventricular dysfunction or intracardi... VO - IS - SP - OP - KW - Pulmonary embolism; Home treatment; Right ventricular dysfunction; Management trial; Rivaroxaban; Risk stratification; OUTPATIENT TREATMENT; INPATIENT TREATMENT; EUROPEAN-SOCIETY; MANAGEMENT; HOSPITALIZATION; THROMBOSIS; 3126 Surgery, anesthesiology, intensive care, radiology; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -