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T1  - Early-life formula feeding is associated with infant gut microbiota alterations and an increased antibiotic resistance load 
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UR  - http://hdl.handle.net/10138/341604 
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A1  - Parnanen, Katariina M. M.; Hultman, Jenni; Markkanen, Melina; Satokari, Reetta; Rautava, Samuli; Lamendella, Regina; Wright, Justin; McLimans, Christopher J.; Kelleher, Shannon L.; Virta, Marko P. 
A2  -  
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Y1  - 2022 
LA  - eng 
AB  - Background Infants are at a high risk of acquiring fatal infections, and their treatment relies on functioning antibiotics. Antibiotic resistance genes (ARGs) are present in high numbers in antibiotic-naive infants' gut microbiomes, and infant mortality caused by resistant infections is high. The role of antibiotics in shaping the infant resistome has been studied, but there is limited knowledge on other factors that affect the antibiotic resistance burden of the infant gut. Objectives Our objec... 
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KW  - antibiotic resistance; neonate; infant formula; metagenomics; bioinformatics; microbiome; human milk; milk fortifier; pediatrics; ANTIMICROBIAL RESISTANCE; READ ALIGNMENT; RIBOSOMAL-RNA; ENTEROBACTERIACEAE; IDENTIFICATION; INTEGRONS; INSIGHTS; MODELS; MILK; 3111 Biomedicine; 3123 Gynaecology and paediatrics 
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