TY - T1 - Effect measures, their estimation and interpretation : Applications to pneumococcal conjugate vaccination SN - / UR - URN:ISBN:978-951-51-7691-2; http://hdl.handle.net/10138/336415 T3 - A1 - Rinta-Kokko, Hanna A2 - PB - Helsingin yliopisto Y1 - 2022 LA - eng AB - The direct and indirect effects of pneumococcal vaccination on an individual and the population are of great interest. This study focuses on the definition, estimation and interpretation of different effect measures of vaccines and vaccination against pneumococcal colonisation and disease. Vaccine efficacy, effectiveness and impact are considered as epidemiological parameters of interest which are estimated using observations gathered according to some study design. In this thesis, vaccine eff... VO - IS - SP - OP - KW - kansanterveystiede N1 - PP - ER -