TY - T1 - Effect of PREP-modifications on autophagy SN - / UR - URN:NBN:fi-fe201801151394; http://hdl.handle.net/10138/230903 T3 - A1 - Huovila, Tiina A2 - PB - Helsingfors universitet Y1 - 2017 LA - eng AB - Autophagy is a pathway for cells to degrade intracellular components that are no longer needed or are detrimental for the cells. It is essential for cell homeostasis and survival and has been related to various diseases and pathophysiology. Autophagy is a complex process and there are still several unclear und unknown aspects to it. Regulation of autophagy is essential to prevent unwanted and escess activation, and several pathways and molecules, both stimulatory and inhibitory, are included. Di... VO - IS - SP - OP - KW - Bcl-2; Beclin 1; HEK-293; KYP-2047; autophagy; prolyl oligopeptidase; immunofluorescence staining; confocal microscopy; colocation analysis; autofagia; prolyylioligopeptidaasi; immunofluoresenssivärjäys; konfokaalimikroskopia; kolokalisaatioanalyysi; Farmakologi; Pharmacology; Farmakologia N1 - PP - ER -