TY  -  
T1  - Effect of headspace gas on nucleation of amorphous paracetamol 
SN  -  /  
UR  - http://hdl.handle.net/10138/312183 
T3  -  
A1  - Palomäki, Emmi A. K.; Yliruusi, Jouko K.; Ehlers, Henrik 
A2  -  
PB  -  
Y1  - 2019 
LA  - eng 
AB  - In this paper, the effect of the gaseous environment on recrystallization of amorphous paracetamol was investigated. The experiments were conducted with a headspace gas consisting of dry air, dry carbon dioxide, dry nitrogen and humid air in four temperatures ranging from 5 degrees C below onset of T-g to 5 degrees C above onset of T-g. The recrystallization was monitored using Raman spectroscopy and subsequent multivariate analysis. In temperatures below onset of T-g, the presence of oxygen del... 
VO  -  
IS  -  
SP  -  
OP  -  
KW  - Amorphism; Crystallization; Nucleation; Raman spectroscopy; Sorption; Paracetamol; RAMAN-SPECTROSCOPY; SURFACE CRYSTALLIZATION; GLASS-TRANSITION; PHYSICAL STABILITY; INDOMETHACIN; DYNAMICS; MOBILITY; FORMS; STATE; WATER; 317 Pharmacy 
N1  -   
PP  -  
ER  -