TY  -  
T1  - Effects of CDNF in experimental models of Huntington´s disease 
SN  -  /  
UR  - URN:ISBN:978-951-51-7741-4; http://hdl.handle.net/10138/336725 
T3  -  
A1  - Stepanova, Polina 
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PB  -  
Y1  - 2021 
LA  - en 
AB  - Parkinson’s disease (PD) and Huntington’s disease (HD) are characterized by loss of function or death of definite cell populations in the basal ganglia. HD is triggered by an expanded polyglutamine tract (glutamine repeats) in the huntingtin protein, leading to misfolding of the protein and subsequent accumulation of mutant huntingtin (mHtt) in the nuclei of different types of neurons. In contrast, in PD, dopamine (DA) neurons in the substantia nigra pars compacta (SNpc) degenerate; moreover, th... 
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OP  -  
KW  - pharmacy 
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