TY - T1 - Electrokinetic characterization of extracellular vesicles with capillary electrophoresis : A new tool for their identification and quantification SN - / UR - http://hdl.handle.net/10138/332354 T3 - A1 - Morani, Marco; Duc Mai, Thanh; Krupova, Zuzana; Defrenaix, Pierre; Multia, Evgen; Riekkola, Marja-Liisa; Taverna, Myriam A2 - PB - Y1 - 2020 LA - eng AB - This work reports on the development of the first capillary electrophoresis methodology for the elucidation of extracellular vesicles' (EVs) electrokinetic distributions. The approach is based on capillary electrophoresis coupled with laser-induced fluorescent (LIF) detection for the identification and quantification of EVs after their isolation. Sensitive detection of these nanometric entities was possible thanks to an 'inorganic-species-free' background electrolyte. This electrolyte was made u... VO - IS - SP - OP - KW - Capillary electrophoresis; LIF detection; Membrane labeling; Extracellular vesicles; FLOW-CYTOMETRY; SEPARATION; PARTICLES; NANOPARTICLES; SIZE; EXOSOMES; BEHAVIOR; MARKERS; 116 Chemical sciences N1 - PP - ER -