TY - T1 - Elevated Systemic IL-10 Levels Indicate Immunodepression Leading to Nosocomial Infections after Aneurysmal Subarachnoid Hemorrhage (SAH) in Patients SN - / UR - http://hdl.handle.net/10138/315260 T3 - A1 - Chaudhry, Shafqat Rasul; Kahlert, Ulf Dietrich; Kinfe, Thomas Mehari; Lamprecht, Alf; Niemelä, Mika; Hänggi, Daniel; Muhammad, Sajjad A2 - PB - Y1 - 2020 LA - eng AB - Background: Aneurysmal subarachnoid hemorrhage (SAH) is a highly complex disease with very high mortality and morbidity. About one-third of SAH patients suffer from systemic infections, predominantly pneumonia, that can contribute to excess mortality after SAH. Immunodepression is probably the most important mechanism leading to infections. Interleukin-10 (IL-10) is a master regulator of immunodepression, but it is still not clear if systemic IL-10 levels contribute to immunodepression, occurren... VO - IS - SP - OP - KW - subarachnoid hemorrhage; cytokine; anti-inflammatory; early brain injury; stroke; aneurysm; inflammation; cerebral vasospasm; clinical outcome; complications; CEREBROSPINAL-FLUID; INTERLEUKIN-10; PREDICTORS; CYTOKINES; 1182 Biochemistry, cell and molecular biology N1 - PP - ER -