TY - T1 - Errors-in-Variables Modeling of Personalized Treatment-Response Trajectories SN - / UR - http://hdl.handle.net/10138/331683 T3 - A1 - Zhang, Guangyi; Ashrafi, Reza A.; Juuti, Anne; Pietiläinen, Kirsi; Marttinen, Pekka A2 - PB - Y1 - 2021 LA - eng AB - Estimating the impact of a treatment on a given response is needed in many biomedical applications. However, methodology is lacking for the case when the response is a continuous temporal curve, treatment covariates suffer extensively from measurement error, and even the exact timing of the treatments is unknown. We introduce a novel method for this challenging scenario. We model personalized treatment-response curves as a combination of parametric response functions, hierarchically sharing info... VO - IS - SP - OP - KW - Trajectory; Measurement errors; Mathematical model; Informatics; Market research; Data models; Blood; Treatment-response trajectories; Bayesian methods; errors-in-variables; hierarchical models; Gaussian processes; wearable self-monitoring devices; time-series data; 3111 Biomedicine; 113 Computer and information sciences N1 - PP - ER -