TY - T1 - Establishment of a spontaneously transformed cell line (JU-PI) from a myxoinflammatory fibroblastic sarcoma SN - / UR - http://hdl.handle.net/10138/299676 T3 - A1 - Fagerstedt, K.W.; Salonen, T.; Zhao, F.; Kytölä, S.; Böhling, T.; Andersson, L.C. A2 - PB - Y1 - 2018 LA - eng AB - Myxoinflammatory fibroblastic sarcoma is a soft-tissue neoplasm most frequently found in the distal extremities of middle-aged adults. Most myxoinflammatory fibroblastic sarcoma are low-grade tumors with propensity for local recurrence after incomplete removal. We report a myxoinflammatory fibroblastic sarcoma which developed in the foot of a 41-year-old male and showed an exceptionally aggressive course with metastatic spread and fatal outcome within 16 months. We managed to establish a spontan... VO - IS - SP - OP - KW - dacarbazine; doxorubicin; etoposide; ifosfamide; transcription factor; transcription factor TFE3; unclassified drug; vincristine; antineoplastic agent; mesna; vincristine, abdominal tumor; adult; Article; cancer palliative therapy; cancer radiotherapy; case report; cell growth; chromosome 3; chromosome rearrangement; chromosome translocation; clinical article; clinical feature; comparative genomic hybridization; disease course; disease exacerbation; DNA isolation; fibrosarcoma; fibrosarcoma cell line; foot injury; gene activation; gene expression; human; human cell; human tissue; immunohistochemistry; JU-PI cell line; leg amputation; lung metastasis; male; microsatellite marker; myxoinflammatory fibroblastic sarcoma; patient history of surgery; polymerase chain reaction; priority journal; recurrent disease; retroperitoneal cancer; scar tissue; transmission electron microscopy; treatment response; tumor growth; whole body CT; cell proliferation; gene translocation; genetics; karyotype; mortality; pathology; primary cell culture; procedures; soft tissue tumor; transformed cell line; tumor recurrence, Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Transformed; Cell Proliferation; Dacarbazine; Doxorubicin; Fibrosarcoma; Humans; Ifosfamide; Karyotype; Male; Mesna; Neoplasm Recurrence, Local; Primary Cell Culture; Soft Tissue Neoplasms; Translocation, Genetic; Vincristine; 3122 Cancers N1 - PP - ER -