TY - T1 - Evaluation of a standardized protocol for thrombin generation using the calibrated automated thrombogram : A Nordic study SN - / UR - http://hdl.handle.net/10138/314537 T3 - A1 - Ljungkvist, Marcus; Strandberg, Karin; Berntorp, Erik; Chaireti, Roza; Holme, Pål Andre; Larsen, Ole Halfdan; Lassila, Riitta; Jouppila, Annukka; Szanto, Timea; Zetterberg, Eva A2 - PB - Y1 - 2019 LA - eng AB - Introduction The thrombin generation assay-calibrated automated thrombogram (TGA-CAT) method is used to measure the overall coagulation capacity in plasma. However, the method is still considered to be a research tool, mainly because of its' lack of standardization. Aim Our study aimed to further raise the standardization level for the TGA-CAT method by evaluating a detailed standardization protocol and three reference plasmas' (RP)s ability to normalize results. Methods Six Nordic centres parti... VO - IS - SP - OP - KW - haemophilia; normalization; reference plasma; standardization; test of agreement; thrombin generation assay; RESISTANT RULES; HEMOPHILIA-A; ANTICOAGULANTS; VARIABLES; ASSAY; 3121 General medicine, internal medicine and other clinical medicine N1 - PP - ER -